Svitlana Prylutska

Oleh Lushchak

Olena Fedorenko

Alina Savotchenko

Olga Kopach

Oleg Tsupykov

Rostyslav Bilyy, Ph.D.

Senior Researcher, 
Institute of Cell Biology,  
National Academy of Sciences of Ukraine 
Associate Professor, 
Department of Cytology, Histology, Embryology, Danylo Halytsky Lviv National Medical University

Education

Ph.D. in Cytology, Cell Biology, and Histology 
Institute of Cell Biology, NAS of Ukraine, Lviv, Ukraine
Thesis Title: “Cell membrane glycoproteins during apoptosis: detection, characteristic, biomedical aspects of study”
M.S. in Biochemistry, Ivan Franko Lviv National University, Lviv, Ukraine.

Research interests

Study of cell surface changes at cell death, and their implication in autoimmunity, intercellular and host-pathogen interactions. 
Study of the nanocomposite’s interaction with plasma membrane during cell death.

Publications

  1. Schauer C, Janko C, Munoz LE, Zhao Y, Kienhöfer D, Frey B, Lell M, Manger B, Rech J, Naschberger E, Holmdahl R, Krenn V, Harrer T, Jeremic I, Bilyy R, Schett G, Hoffmann M, Herrmann M. Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines. Nature Medicine 2014; advance online publication, doi:10.1038/nm.3547.
  2. Tomin A, Dumych T, Tolstyak Y, Kril I, Mahorivska I, Bila E, Stoika R, Herrmann M, Kit Y, Bilyy R. Desialylation of dying cells with catalytically active antibodies possessing sialidase activity facilitates their clearance by human macrophages. Clinical & Experimental Immunology 2014, advance online publication, doi:10.1111/cei.12312.
  3. Magorivska I, Jeremic I, Herman S, Munoz LE, Bilyy R, Herrmann M. 1.58 rheumatoid factor binding is influenced by the N-Glycans of their IGG targets. Annals of the Rheumatic Diseases 2014; Ann Rheum Dis 2014;73:A25 doi:10.1136/annrheumdis-2013-205124.57
  4. Brument S, Sivignon A, Dumych TI, Moreau N, Roos G, Guérardel Y, Chalopin T, Deniaud D, Bilyy RO, Darfeuille-Michaud A, Bouckaert J, Gouin SG. Thiazolylaminomannosides As Potent Antiadhesives of Type 1 Piliated Escherichia coli Isolated from Crohn’s Disease Patients. J of Medicinal Chemistry 2013; 56:5395-5406.
  5. Chaurio R, Janko C, Schorn C, Maueroder C, Bilyy R, Gaipl U, Schett G, Berens C, Frey B, Munoz LE. UVB-irradiated apoptotic cells induce accelerated growth of co-implanted viable tumor cells in immune competent mice. Autoimmunity 2013; 46:317-322.
  6. Bilyy RO, Shkandina T, Tomin A, Munoz LE, Franz S, Antonyuk V, Kit YY, Zirngibl M, Furnrohr BG, Janko C, Lauber K, Schiller M, et al. Macrophages discriminate glycosylation patterns of apoptotic cell-derived microparticles. J Biological Chemistry 2012; 287:496-503.
  7. Prylutska S, Bilyy R, Overchuk M, Bychko A, Andreichenko K, Stoika R, Rybalchenko V, Prylutskyy Yu, Tsierkezos NG, Ritter U. Water-Soluble Pristine Fullerenes C60 Increase the Specific Conductivity and Capacity of Lipid Model Membrane and form the Channels in Cellular Plasma Membrane. J of Biomedical Nanotechnology 2012; 8:522-527.
  8. Shkandina T, Herrmann M, Bilyy R. Sweet kiss of dying cell: Sialidase activity on apoptotic cell is able to act toward its neighbors. Autoimmunity 2012; 45:574-578.
  9. Bilyy R, Tomin A, Mahorivska I, Shalay O, Lohinskyy V, Stoika R, Kit Y. Antibody-mediated sialidase activity in blood serum of patients with multiple myeloma. J of Molecular Recognition 2011; 24:576-584.
  10. Meesmann HM, Fehr E-M, Kierschke S, Herrmann M, Bilyy R, Heyder P, Blank N, Krienke S, Lorenz H-M, Schiller M. Decrease of sialic acid residues as an eat-me signal on the surface of apoptotic lymphocytes. J Cell Sciences 2010; 123:3347-3356.